• In the present study it was

  2021-03-02

  

  In the present study, it was particularly of interest that intravesical administration of PGE2 evoked ONO-8130-reversible rapid phosphorylation of ERK in the L6 spinal cord. Detection of phosphorylated ERK is now often used as a marker for somatic and visceral nociception, including lactone australi

• br Funding This work was supported by the PACA Region

  2021-03-02

  

  Funding This work was supported by the PACA Region and Avignon Université. Acknowledgements Introduction Cancer is a pivotal health problem all over the world [1]. In spite of enormous advances achieved in diagnosis and treatment over the past decades, it still accounts for over 22000 deat

• br Materials and methods br Results discussion br

  2021-03-02

  

  Materials and methods Results + discussion Conclusions We have demonstrated the systematic optimization of the functional folding of a CF synthesized GPCR. The approach addresses central issues relevant for many membrane proteins such as disulfide bridge formation, proper hydrophobic enviro

• br Results br Discussion The

  2021-03-02

  

  Results Discussion The origin and fate of Tfh cells has been intensely studied since their first description 14 years ago (Breitfeld et al., 2000, Schaerli et al., 2000). Although mice engineered to report BCL6 (Kitano et al., 2011, Liu et al., 2012) and interleukin-21 (IL-21) (Lüthje et al.,

• br Conclusions This study showed that

  2021-03-02

  

  Conclusions This study showed that in EOC cells, tyrosine kinase receptor DDR1 was expressed mainly in EOC Anastrozole with an Epithelial phenotype. The repressed expression of DDR1 in EOC cells with Mesenchymal phenotype could be due to the higher CpG methylation levels observed at the promoter

• Survival analysis has been widely used in

  2021-03-02

  

  Survival analysis has been widely used in medical science, economics, finance, and social science, among others. In many studies, survival data have primary outcomes or responses that are subject to censoring. The Cox model [7], [8] is the most commonly used regression model for survival data, and t

• Inopportunely normal aging brings about decreases in frontal

  2021-03-02

  

  Inopportunely, normal aging brings about decreases in frontal D1 receptor densities and a gradual decline in postsynaptic markers of dopamine in striatal, neocortical, and limbic areas of the Spermine NONOate mg (Bäckman et al., 2006, de Keyser et al., 1990, Karrer et al., 2017, Suhara et al., 1991

• br Dienogest DNG Dienogest is a nortestosterone

  2021-03-02

  

  Dienogest (DNG) Dienogest is a 19-nortestosterone derivative with two special structural changes [Fig. 1a]: [a] At the cabon-17 position there is a cyanomethyl group instead of an ethinyl group; [b] A double bond is present between carbons 9 and 10. DNG is the only progestogen that combines prope

• Estrogens Definition and history The term estrogens refers

  2021-03-02

  

  Estrogens: Definition and history The term “estrogens” refers to a group of female hormones, including estrone, estradiol, estriol, and estretrol (Fig. 1). Chemically, estrogens belong to the family of organic compounds known as steroids. As such, their core structure is composed of 17 carbon-carbo

• br Materials and methods br Results br Discussion

  2021-03-02

  

  Materials and methods Results Discussion DUSP1 is a member of the subfamily of the Dusl specific phosphatases (DUSPs). High levels of DUSP1 observed in lung, liver and placenta, and low levels have been found in the 93 6 and kidney. DUSP1 has been shown to be elevated in various diseases [

• In pregnancy maternal uterine spiral artery

  2021-03-01

  

  In pregnancy, maternal uterine spiral artery (SA) remodeling is essential for ensuring efficient blood flow to the developing fetus. A subset of CD49a+Eomes+ decidual NK AMG 337 (dNK) that actively secretes GFs, such as pleiotrophin and osteoglycin, have recently been described in humans and in mice

• br Materials and methods br Results br Discussion

  2021-03-01

  

  Materials and methods Results Discussion Drug of abuse induces widespread xanthine oxidase changes in the molecular and cellular functions in circuits between VTA and its neighbored regions such as NAC, and amygdala. It is belived that these changes result behavioral phenotype that charact

• Structural changes within the heteromer induced

  2021-03-01

  

  Structural changes within the heteromer induced by agonist administration show a high level of complication. The presented results obtained in quantitative FLIM-FRET measurements with two selective ligands match the qualitative conclusions indicated by changes in the intracellular calcium level. The

• In anticipation of an approach based on

  2021-03-01

  

  In anticipation of an approach based on modification of the cyclohexylacetic leukotriene receptor antagonist subunit of 1 as a means of improving permeability, a set of analogs were prepared to map out the optimum display of the acidic functionality. Homologated acids 25 and 26 were found to be equi

• br Contributors br Acknowledgements br Introduction

  2021-03-01

  

  Contributors Acknowledgements Introduction Pemphigus disorders are characterized by autoantibodies binding to desmosomes between epidermal cells, resulting in the loss of cell to cell adhesion and blister formation. In pemphigus foliaceus, autoantibodies predominantly bind to desmoglein 1,

14541 records 693/970 page Previous Next First page 上5页 691692693694695 下5页 Last page