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Ishita et al studied the anti inflammatory activity
2020-07-27
Ishita et al. studied the anti-inflammatory activity of 9 coumarin derivatives isolated from a 90% methanol fraction of Angelica decursiva traditional used in age old Korean medicine as an antitussive, analgesic, antipyretic, and cough remedy, it was evaluated via inhibition of production of nitric
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The TMS is considered failed
2020-07-27
The TMS is considered failed if either the monitoring application provides to the operator wrong information that do not reflect the real railways status (functional failure), or if the service completely stops being provided (non-functional failure). The architecture currently adopted by ASTS, ther
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Ten studies have examined the
2020-07-27
Ten studies have examined the associations of 5-HTTLPR and COMT Val158Met polymorphisms with alexithymia. Among them, five studies investigated the roles of 5-HTTLPR (Ham et al., 2005; Kano et al., 2012; Mandelli et al., 2013; Porcelli et al., 2015; Terock et al., 2018), and other five studies exami
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Initially the cause of hypoglycemia was not apparent
2020-07-26
Initially, the cause of hypoglycemia was not apparent. There was no detectable lesion in the pancreas on plain computed tomography, and anti-insulin antibody was negative. Eight hours after hospital admission, his son discovered that the patient had accidentally taken glimepiride 3mg/day for 3 days.
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br Discussion Although DNA has
2020-07-25
Discussion Although DNA has a limited chemical stability it has long been known that DNA in blood stains may remain relative stable for weeks, months, or even years at ambient temperature,1, 2, 3, 4, 5, 6 and samples (e.g., reference samples) that have been transferred to a matrix, e.g., FTA® pap
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Although there was little to no expression change observed b
2020-07-25
Although there was little to no expression change observed by TELI of the recA and ruvA genes upon CAA exposure, other specific repair pathways were induced by both CAA and SO and include the SOS-inducible gene sulA, the DNA repair gene ykfG, the mismatch repair gene mutS, the recombination and repa
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Although it is believed that CYP
2020-07-25
Although it is believed that CYP induction is regulated in humans in principle in the same fashion as in animals, some species differences in CYP3A enzymes induction were observed. Rifampicin is known to be a potent inducer of CYP3A4 in human hepatocytes, whereas pregnenolone-16α-carbonitrile (PCN)
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Based on the finding described
2020-07-25
Based on the finding described above, the present study was designed to investigate the effects of specific CRF receptors, CRF1 and CRF2, in the BLA and CeA on the duration of TI in guinea pigs (Cavia porcellus). To this end, we evaluated whether administration of the CRF1 amyloid beta protein anta
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Though limited to a large
2020-07-25
Though limited to a large cohort of self-reported healthy individuals, associations between individual Stattic receptor have been identified which may be clinically significant. Though slight, there is a relationship between the CYP2D6-inferred metabolizer phenotype and the diplotype-predicted acti
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GDC-0834 receptor Although CCR expression clearly identifies
2020-07-25
Although CCR6 expression clearly identifies MBC precursors within the GC, we found that the expression of this chemokine receptor by responding GDC-0834 receptor was not required for MBC differentiation and had no detectable impact on the GC subsets analyzed in this study. Although this is in agree
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Tn5 DNA Library for 50 ng DNA synthesis Introduction Psorale
2020-07-25
Introduction Psoralea corylifolia L. (Leguminosae) is a well-known traditional Chinese medicine, and it has been widely used for the treatment of various diseases like bronchial asthma, leucopenia, vitiligo and psoriasis in East Asian countries (Zhang et al., 1990). Previous studies have reported t
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Low estrogen levels in young
2020-07-24
Low Levofloxacin receptor levels in young women, irrespective of etiology, might have harmful effects on cardiovascular physiology. Indeed, a study in premenopausal women with low estrogen levels owing to hypothalamic hypogonadism showed an increased incidence of angiographic CAD in these women comp
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While we previously demonstrated that
2020-07-24
While we previously demonstrated that TraG is inhibited by specific transglycosylase inhibitors and that enzymatic activity is strongly reduced upon mutation of the potential catalytic core (Arends et al., 2013), the enzymatic mechanism of both domains was not assigned. Here, by mass spectrometry an
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Pursuant to our in vitro data that neutrophilic
2020-07-24
Pursuant to our in vitro data that neutrophilic elastase activated the elastase-dependent oncolytic virus, we initially hypothesized that tumor-infiltrating neutrophils could be the source for elastase in tumor tissue. However, we did not detect neutrophils in the PANC-1 tumor tissue where we observ
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To analyze EBI expression and its function in T cells
2020-07-24
To analyze EBI2 expression and its function in T cells in vivo, we created an EGFP reporter/knockout mouse strain, termed EBI2EGFP. This mouse strain in heterozygous configuration allows for a systematic analysis of the expression of EBI2 in distinct cell types in steady-state and under inflammatory
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