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As the COMT enzyme is primarily
2019-09-11
As the COMT enzyme is primarily related to prefrontal dopamine degradation (e.g., Yavich et al., 2007), the present study supports the notion that prefrontal dopamine modulates retention of fear extinction rather than within-session extinction (Abraham et al., 2014).
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TraM is one of two transfer
2019-09-10
TraM is one of two transfer proteins from pIP501 T4SS that have structural similarity to the A. tumefaciens VirB8 protein (Fercher et al., 2016, Goessweiner-Mohr et al., 2013), a central member of the inner membrane complex (Bailey et al., 2006, Guglielmini et al., 2014, Trokter et al., 2014).
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Etoricoxib RQ What are the different factors that influence
2019-09-09
RQ2: What are the different factors that influence the decision to choose among different component origins?
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Eltrombopag Olamine Acknowledgements Introduction Three st
2019-09-07
Acknowledgements Introduction Three structurally related fungal metabolites have been isolated from chloroform extracts of submerged rice cultures of Aspergillus terreus 23-1 from stored unhulled rice in Taiwan; these were named territrems A–C to indicate their biological origin (A. terreus) and their tremorgenic activity (Ling et al., 1979, Ling et al., 1984, Ling, 1994).
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Thermodynamic modeling Selection of
2019-09-06
Thermodynamic modeling Selection of data The solutes were selected based on the set of data needed to evaluate the CPA-EoS for prediction of their solubility in CO2 + cosolvent, as shown in Fig. 1.
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Results Discussion PKR is activated by
2019-09-05
Results Discussion PKR is activated by viral dsRNA and exerts its antiviral effect through phosphorylation of eIF2a.
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To simulate the inhibition of the enzyme by
2019-09-04
To simulate the inhibition of the enzyme by organophosphorus, carbamate insecticides or nerve agents, a reversible cholinesterase inhibitor physostigmine was used for most experiments for safety reasons.
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ATRX belongs to the switch sucrose non fermenting SWI
2019-09-03
ATRX belongs to the switch/sucrose non-fermenting (SWI/SNF) chromatin remodeling family, mutations in which cause syndromal mental retardation and downregulation of α-globin expression (Gibbons et al., 1995).
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Furthermore down regulation of Cpt a
2019-09-02
Furthermore, down-regulation of Cpt1a, ApoE, Fasn, Pxr, and Srebp-1 genes indicates a down-regulation of lipid metabolism associated genes while Fatp1 is up-regulated and indicates an increase in fatty Cevimeline hydrochloride hemihydrate transport genes involved in accumulation [84,85].
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The IL family consists of nine related molecules IL IL
2019-08-30
The IL-10 family consists of nine related molecules: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28α, IL-28β, and IL-29 [34].
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In the present study we first examined the in vivo
2019-08-29
In the present study, we first examined the in vivo and ex vivo effects of androgens on ep1 BMS-833923 in the olfactory rosette of male B. sinensis.
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We have previously reported DAPK inhibitors discovered
2019-08-28
We have previously reported DAPK inhibitors discovered through our structure-based virtual screening (SBVS) research program.
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Dienogest DNG Dienogest is a
2019-08-27
Dienogest (DNG) Dienogest is a 19-nortestosterone derivative with two special structural changes [Fig. 1a]: [a] At the cabon-17 position there is a cyanomethyl group instead of an ethinyl group; [b] A double bond is present between carbons 9 and 10.
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For in vitro expression analysis of CXCL
2019-08-26
For in vitro expression analysis of CXCL8 and CXCRs by stimulated leucocytes, peripheral blood leucocytes (PBLs) were isolated using Percoll density gradient centrifugation as described earlier .
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In another study Nutlin a mediated p
2019-08-24
In another study, Nutlin-3a-mediated p53 activation induced strong negative impact on NF-κB signaling in LPS-stimulated neutrophils and macrophages [34]. Nutlin-3a limited cellular immune response to LPS, partly by attenuating DNA binding activity of NF-κB and impairing transcription of its target cytokine genes.
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